Welcome to the NEXT project


App-Bio-Tissue-Engineering-01The Nano Engineering for Cross Tolerance: new approach for bioengineered, vascularised, chimeric islet transplantation in non-immunosuppressed hosts (NEXT) project aims at developing the next generation of chimeric pancreatic islet for diabetes 1 treatment. NEXT will provide a 360° solution to the pitfalls of current methodology for pancreatic islet transplantation:
i) Nano technologies, to engineer donor cell surfaces in order to derange recognition and suppress their rejection;
ii) Advanced tissue engineering methods, to assemble bio synthetic islet, enriched by chimeric microvasculature;
iii) Innovative double immune-suppressive strategy using immunosuppressive nano peptides

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The NEXT project is funded by the European Union’s ‘Seventh Framework’ Programme for research, technological development and demonstration under Grant Agreement n° HEALTH.2013.1.3-2-602235 from 2013-10-01 to 2017-09-30